应张朝阳教授的邀请，美国德克萨斯州大学San Antonio分校电气与计算机工程系的Yufei Huang教授携夫人Jianqiu Zhang教授近日对信息与通信工程研究所进行了学术访问。
6月27日下午，Huang教授和Zhang教授一同在信电楼四楼学术厅为广大师生做了题为《Signal Processing and Computational Systems Biology》的学术报告。Huang教授和Zhang教授的主要研究兴趣是计算生物学。报告中，他们以疟疾病毒基因、癌症预后等研究为实例，介绍了他们如何运用统计信号处理的方法对生命科学中各种现代实验方法获取的海量数据进行智能的分析处理，从而为科学研究和疾病诊断治疗提供重要的信息。报告生动有趣，深入浅出，令广大师生开拓了学术视野。我所张朝阳教授、仇佩亮教授、黄爱苹教授等教师及研究生听取了学术报告，并与两位教授进行了热烈的讨论。会后，Huang教授夫妇在张朝阳教授的陪同下参观了我所的有关实验室。
附：报告摘要
Title: Signal Processing and Computational Systems Biology
Speaker: Prof. Yufei Huang, Dept. of Electrical and Computer Engineering, University of Texas at San Antonio, Texas, USA
Abstract: Biomedical research has entered an exciting era of systems biology. In contrast to the experimental-centric approach of the traditional biomedical research, systems biology relies on iterative application of biomedical experiments and knowledge with mathematical modeling and systems control theory to investigate interplays of molecules and cells in time and space to determine functioning of a complex biological system. Translation of such knowledge into medicine is and will continue to revolutionize disease diagnosis and prognosis, medical therapy, prevention, drug discovery, and drug design.
In this talk, I will first explain the importance of signal processing in system biology research by introducing the concept of systems biology and various types of high throughput biological data. I will then briefly discuss the signal processing applications to reconstruct genetic regulatory networks of malaria using gene sequences and microarray expression data, cancer prognosis based on mass spectrometry data and time dependent genetic regulatory module discovery using time series microarray data. I will conclude the talk by providing outlooks of systems biology research.